A precise cause has not been located. However, there are several factors that may contribute to the disease.
Genes: A genetic component to the disease has been shown.According to the National Institute of Mental Health,a person who has a parent with Mania has a 15-30 % chance of developing this condition.The risk increases to 50 to 75% when both parents have bipolar disorder.Other studies show that the disease is polygenic, that is, it is a disease not carried by one specific gene, but caused by an interaction of genes in several different locations in the body.
Researchers have recently created the first comprehensive map of genetic pathways identified with bipolar disorder. This accomplishment will lead to more effective diagnosis and treatment of the disease.
Neurotransmitters: An abnormal neurotransmitter system seems to be partially the cause of Manic disorder. When neurotransmitters like serotonin are imbalanced, the mood stabilizing function of the brain is in jeopardy.
More on Bipolar Disorder at
http://www.help-your-child-with-anger.com/bipolar-disorder.html
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